"A webcomic of romance, sarcasm, math, and language." M-W-F comic... Very sciency, very funny. The art is not much to talk about, as author Randall Munroe adheres for the most part to a stick figure format, though it suits the comic well. I'm not sure it would be any better otherwise.
Ok. Evan Dahm is a champion. I really, reaaaally recommend reading these. Order to read them in: Rice Boy, Order of Tales, the short stories collection, then Vattu (the current comic being worked on).
Rather than having a humorous comic, these tell awesome, epic stories. The art is just incredible: Rice Boy has an odd style at first, but is greatly detailed with awesome, colorful landscapes that meet somewhere between painterly and cartoonish. Order of Tales is drawn completely in black and white, with amazing shadow work and... just... It's awesome. Vattu has a similar artsistic style to Rice Boy.
The comics all take place in an overarching story on the continent of Overside, and are very indepth, yet not confusing... and... Ok, I'll stop, I don't want to make this too long
Another videogame based blog/comic. Great art, especially in the facial expressions. Oh GOD, the facial expressions xD Quite a funny comic, though for some of them I suppose you have to have a certain taste in humor.
Not much else to say about it, other than the fact that it seems to also have a pretty good community forum.
AKA: Dinosaur Comics!
I love these ones. Each comic consists of the same several panelled drawing, with only the text changing between them. And boy, is there a helluvalot of text sometimes. This comic spans quite a range, from philosophical to nonsensical: conversations about the universe, Batman nappytiems, and lesbian relationships between two male dinosaurs... Sometimes it gets a little weird, but that makes it all the better.
Welp, that's all I've got for now. I'll be back with more >:D